OPA1 polyclonal, anti-human, mouse, rat

Background:
This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms: BERHS, MGM1, MTDPS14, NPG, NTG, largeG

Cellular Location: Mitochondrion inner membrane Mitochondrion intermembrane space Single-pass membrane protein

Immunogen:
Recombinant protein of human OPA1

Gene Symbol: OPA1

Gene ID: 4976

Swiss prot: O60313

Calculated MW: 112kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.