OPA3 polyclonal, anti-human, mouse, rat

Background:
The mouse ortholog of this protein co-purifies with the mitochondrial inner membrane. Mutations in this gene have been shown to result in 3-methylglutaconic aciduria type III and autosomal dominant optic atrophy and cataract. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative Name:
Optic atrophy 3 protein

Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Specificity: OPA3 polyclonal antibody detects endogenous levels of OPA3 protein.

Immunogen:
Recombinant protein of human OPA3.

MW: ~ 20 kDa

Swis Prot.: Q9H6K4

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.