OPCML polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Opioid-binding protein/cell adhesion molecule-like(OPCML),(also called opioid-binding cell adhesion molecule(OBCAM). OPCML is a member of the IgLON family of immunoglobulin(Ig) domain-containing glycosylphosphatidylinositol(GPI)-anchored cell adhesion molecules, as an excellent candidate for the 11q25 ovarian cancer TSG in EOC. The OPCML gene comprises 7 exons, spans approximately 600 kb, and is transcribed from telomere to centromere . And due to the lack of transmembrane domains necessary for signal transduction, it is improbable that OBCAM acts independently as an opioid receptor; more likely, it plays an important accessory role in opioid receptor function.

Description:
Rabbit IgG polyclonal antibody for Opioid-binding protein/cell adhesion molecule (OPCML) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
GM181 antibody, IgLON family member 1 antibody, IGLON1 antibody, OBCAM antibody, OPCM antibody, OPCM_HUMAN antibody, OPCML antibody, Opiate binding cell adhesion molecule antibody, Opioid binding cell adhesion molecule antibody, Opioid binding protein/cell adhesion molecule antibody, Opioid binding protein/cell adhesion molecule-like antibody, Opioid binding protein/cell adhesion molecule-like preprotein antibody, Opioid-binding cell adhesion molecule antibody, Opioid-binding protein/cell adhesion molecule antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human OPCML(294-312aa YTCVATNKLGNTNASITLY), identical to the related rat and mouse sequences.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human.
Predicted to work with: mouse, rat.

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.