OPG polyclonal antibody, anti-human, mouse

Background:
TNF receptor superfamily member 11b encoded by TNFRSF11B is a member of the TNF-receptor superfamily. TNF receptor superfamily member 11b is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. TNF receptor superfamily member 11b specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that TNF receptor superfamily member 11b and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of TNFRSF11B have been reported, but their full length nature has not been determined.

Research Area: Cardiovascular

Synonyms: TNFRSF11B, OCIF, OPG, Tumor necrosis factor receptor superfamily member 11B, Osteoclastogenesis inhibitory factor, Osteoprotegerin

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year