OPRD1 polyclonal, anti-human, mouse, rat

Background:
Endogenous opioid peptides and opiates, like morphine, transmit their pharmacological effects through membrane bound opioid receptors. Pharmacological studies and molecular cloning have led to the identification of three different types of opioid receptor, mu-type, delta-type and kappa-type, also designated MOR-1, DOR-1 and KOR-1, respectively. MOR-1 is a receptor for beta-endorphin, DOR-1 is a receptor for enkephalins, and KOR-1 is a receptor for dynorphins. The three opioid receptor types are highly homologous and belong to the superfamily of G protein-coupled receptors. Opioid receptors have been shown to modulate a range of brain functions, including instinctive behavior and emotions. This regulation is thought to involve the inhibition of neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance.

Alternative Name:
D-OR-1, DOR-1, OPRD1, D-OR-1, Delta type opioid receptor, Delta type opioid receptor DOR 1, Delta type opioid receptor DOR1, Delta-type opioid receptor, DOR 1, DOR-1, DOR1, mDOR, Nbor, Opioid receptor delta 1, OPRD 1, OPRD, OPRD, Oprd1,

Application Dilution:
WB:1:1,000
FC:1:50-1:100

Specificity: OPRD1 polyclonal antibody detects endogenous levels of OPRD1 protein.

Immunogen:
recombinant protein

MW: 40 kDa

Swiss-Prot: P41143(Human) P32300(Mouse) P33533(Rat)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.