OPRM1 polyclonal, anti-human

Background:
Receptor for endogenous opioids such as beta-endorphin and endomorphin. Receptor for natural and synthetic opioids including morphine, heroin, DAMGO, fentanyl, etorphine, buprenorphin and methadone.Agonist binding to the receptor induces coupling to an inactive GDP-bound heterotrimeric G-protein complex and subsequent exchange of GDP for GTP in the G-protein alpha subunit leading to dissociation of the G-protein complex with the free GTP-bound G-protein alpha and the G-protein beta-gamma dimer activating downstream cellular effectors.

Synonyms: OPRM1, MOR1, hMOP, Mu-type opioid receptor

Cellular Location: Cell membrane

Immunogen:
A synthetic peptide of human OPRM1

Gene Symbol: OPRM1

Gene ID: 4986

Swiss prot: P35372

Calculated MW: 45/50/55/36/20/11kDa

Recommended dilution:
IHC 1:50-200

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.