Opticin polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS60333
Background:
Opticin, also known as OPTC or OPT, is a 332 amino acid protein that is secreted into the extracellular matrix and contains seven LRR repeats. Expressed in skin and fetal liver and also present in ocular tissues, such as the retina, cornea and iris, opticin functions to bind collagen fibrils and, via this interaction, is thought to regulate fibril spacing, morphology and organization. Opticin is subject to post-translational O-glycosylation and may be associated with the pathogenesis of primary open angle glaucoma.
Alternative Name:
Oculoglycan, OPTC, OPT
Application Dilution: WB: 1:500~1:1000
Specificity: Opticin polyclonal antibody detects endogenous levels of Opticin protein.
Immunogen:
A synthetic peptide corresponding to residues in Human Opticin.
MW: ~ 40 kDa
Swis Prot.: Q9UBM4
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Opticin, also known as OPTC or OPT, is a 332 amino acid protein that is secreted into the extracellular matrix and contains seven LRR repeats. Expressed in skin and fetal liver and also present in ocular tissues, such as the retina, cornea and iris, opticin functions to bind collagen fibrils and, via this interaction, is thought to regulate fibril spacing, morphology and organization. Opticin is subject to post-translational O-glycosylation and may be associated with the pathogenesis of primary open angle glaucoma.
Alternative Name:
Oculoglycan, OPTC, OPT
Application Dilution: WB: 1:500~1:1000
Specificity: Opticin polyclonal antibody detects endogenous levels of Opticin protein.
Immunogen:
A synthetic peptide corresponding to residues in Human Opticin.
MW: ~ 40 kDa
Swis Prot.: Q9UBM4
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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