Fliz1 polyclonal, anti-human
€470.00
In stock
SKU
AC-AP69904
Background:
Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity). Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:23932780). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.
Other Names:
ZC3H8; ZC3HDC8; Zinc finger CCCH domain-containing protein 8
Antigen Type: synthetic peptide
Antigen Type: ZC3H8
Gene ID: 84524
Primary Accession: Q8N5P1
Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity). Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:23932780). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.
Other Names:
ZC3H8; ZC3HDC8; Zinc finger CCCH domain-containing protein 8
Antigen Type: synthetic peptide
Antigen Type: ZC3H8
Gene ID: 84524
Primary Accession: Q8N5P1
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