ORC4 Polyclonal Antibody

Background:
The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. This gene encodes a subunit of the ORC complex. Several alternatively spliced transcript variants, some of which encode the same protein, have been reported for this gene.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
Origin recognition complex, subunit 4, S. cerevisiae, homolog of, FLJ46668, HSORC4, ORC 4, ORC 4L, ORC 4P, ORC4, ORC4, ORC4L, ORC4L protein, ORC4P, Origin recognition complex subunit 4 (yeast homolog) like, Origin recognition complex subunit 4, Origin recognition complex subunit 4 like (yeast), Origin recognition complex subunit 4 like, origin recognition complex, subunit 4 homolog, Origin recognition complex, subunit 4, S. cerevisiae, homolog-like

Immunogen: Fusion protein of human ORC4

Swissprot: O43929
Gene Accession: BC005388

Calculated MW: 50 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.44 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.