ORC6 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS71021
Background:
The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.
Alternative Name:
ORC6L, Origin recognition complex subunit 6
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: ORC6 polyclonal antibody detects endogenous levels of ORC6 protein.
Immunogen:
Recombinant protein of human ORC6.
MW: ~ 28 kDa
Swis Prot.: Q9Y5N6
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.
Alternative Name:
ORC6L, Origin recognition complex subunit 6
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: ORC6 polyclonal antibody detects endogenous levels of ORC6 protein.
Immunogen:
Recombinant protein of human ORC6.
MW: ~ 28 kDa
Swis Prot.: Q9Y5N6
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
| Is Featured? | No |
|---|
Write Your Own Review