Orexin R-1 rabbit polyclonal, anti-human, mouse, rat

Backgroud: The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B. [provided by RefSeq, Jan 2009],function:Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Seems to be exclusively coupled to the G(q) subclass of heteromeric G proteins, which activates the phospholipase C mediated signaling cascade.,similarity:Belongs to the G-protein coupled receptor 1 family.,

Synonyms: HCRTR1, Orexin receptor type 1, Ox-1-R, Ox1-R, Ox1R, Hypocretin receptor type 1

Gene Name: HCRTR1

Gene ID: 3061

SwissProt ID: O43613

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.