ORMDL1 polyclonal, anti-human, mouse, rat
€484.00
In stock
SKU
254472
Protein Family: Enzymes
Pathway and Disease: Signaling Molecules and Interaction
Description:
The ORMDL (ORM1-like) family of proteins consist of ORMDL1, ORMDL2 and ORMDL3 that may play roles in gamma-secretase complex maturation. Localized to the membrane of the endoplasmic reticulum, ORMDLs are widely expressed and are implicated in the expression of Presenilin (PSI) which is involved in Alzheimer’s disease (AD). Expression of ORMDL1 is down-regulated in PSI mutations, suggesting a possible role as a therapeutic target for AD. ORMDLs have recently been identified as a potential risk factor for childhood asthma.
Alternate Names: ORMDL1, Adoplin-1, FLJ44364, HSPC202, ORM1-like protein 1
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: NP_057551
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human ORMDL1.
Format: Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Signaling Molecules and Interaction
Description:
The ORMDL (ORM1-like) family of proteins consist of ORMDL1, ORMDL2 and ORMDL3 that may play roles in gamma-secretase complex maturation. Localized to the membrane of the endoplasmic reticulum, ORMDLs are widely expressed and are implicated in the expression of Presenilin (PSI) which is involved in Alzheimer’s disease (AD). Expression of ORMDL1 is down-regulated in PSI mutations, suggesting a possible role as a therapeutic target for AD. ORMDLs have recently been identified as a potential risk factor for childhood asthma.
Alternate Names: ORMDL1, Adoplin-1, FLJ44364, HSPC202, ORM1-like protein 1
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: NP_057551
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human ORMDL1.
Format: Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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