OSBPL2 Polyclonal Antibody

Background:
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although the encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described.

Research Area: Cancer, Cardiovascular, Metabolism, Signal transduction

Synonyms:
FLJ20223, KIAA0772, MGC4307, MGC8342, ORP2, OSBP related protein 2, Oxysterol binding protein like 2, Oxysterol binding protein related protein 2

Immunogen: Fusion protein of human OSBPL2

Swissprot: Q9H1P3
Gene Accession: BC000296

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.14 mg/mL
Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.