OSBPL2 Polyclonal Antibody

Background:
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although the encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described.

Research Area: Cancer, Cardiovascular, Metabolism, Signal transduction

Synonyms:
OSBPL2, DFNA67, DNFA67, ORP-2, ORP2

Immunogen: Recombinant fusion protein of human OSBPL2 (NP_653081.1).

Swissprot: Q9H1P3
Gene ID: 9885

Calculated MW: 53 kDa/55 kDa
Observed MW: 56 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.