OSCAR polyclonal (C-term), anti-human
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In stock
SKU
AC-AP18846b
Catalog Number: AC-AP18846b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB39599
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB39599
Applications: WB
Datasheet
Request Information
Background:
Osteoclasts are multinucleated cells that resorb bone andare essential for bone homeostasis. This gene encodes anosteoclast-associated receptor (OSCAR), which is a member of theleukocyte receptor complex (LRC) protein family that plays criticalroles in the regulation of both innate and adaptive immuneresponses. Different from the other LRC members, OSCAR expressionis detected specifically in preosteoclasts or mature osteoclasts.OSCAR may be an important bone-specific regulator of osteoclastdifferentiation. Multiple alternatively spliced transcript variantsencoding different isoforms have been found for this gene.
Other Names:
Osteoclast-associated immunoglobulin-like receptor, Osteoclast-associated receptor, hOSCAR, Polymeric immunoglobulin receptor 3, PIgR-3, PIgR3, Poly-Ig receptor 3, OSCAR
Target/Specificity:
This OSCAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-231 amino acids from the C-terminal region of human OSCAR.
Antigen Region:
205-231
Antigen Type: Synthetic Peptide
Gene Name: OSCAR
Gene ID: 126014
Primary Accession: Q8IYS5
NCBI Accession: NP_001269278.1;NP_001269279.1;NP_570127.3;NP_573398.2;NP_573399.2;NP_996554.2
Other Accession: NP_570127.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Osteoclasts are multinucleated cells that resorb bone andare essential for bone homeostasis. This gene encodes anosteoclast-associated receptor (OSCAR), which is a member of theleukocyte receptor complex (LRC) protein family that plays criticalroles in the regulation of both innate and adaptive immuneresponses. Different from the other LRC members, OSCAR expressionis detected specifically in preosteoclasts or mature osteoclasts.OSCAR may be an important bone-specific regulator of osteoclastdifferentiation. Multiple alternatively spliced transcript variantsencoding different isoforms have been found for this gene.
Other Names:
Osteoclast-associated immunoglobulin-like receptor, Osteoclast-associated receptor, hOSCAR, Polymeric immunoglobulin receptor 3, PIgR-3, PIgR3, Poly-Ig receptor 3, OSCAR
Target/Specificity:
This OSCAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-231 amino acids from the C-terminal region of human OSCAR.
Antigen Region:
205-231
Antigen Type: Synthetic Peptide
Gene Name: OSCAR
Gene ID: 126014
Primary Accession: Q8IYS5
NCBI Accession: NP_001269278.1;NP_001269279.1;NP_570127.3;NP_573398.2;NP_573399.2;NP_996554.2
Other Accession: NP_570127.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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