OSM human active recombinant protein
€295.00
In stock
SKU
600395
Protein Family: Cytokines
Pathway and Disease: Cell Growth and Death, Signal Transduction, Signaling Molecules and Interaction
Alternate Names: Onc-M, Oncostatin M, OSMDescription:
Oncostatin M (OSM) is a growth regulator produced by a variety of cells and has a wide range of attributed functions. Several of these functions include: inhibition of tumor cell line proliferation, liver development/regeneration, regulation of cytokine production (hematopoiesis and inflammation), bone development and possibly nervous system development. Human OSM is produced in E. coli as a non-glycosylated protein, containing 210 amino acids, with a molecular weight of 23.8 kDa.
Source: E. coli. Endotoxin level as measured by LAL is <0.05ng/ug or <0.5EU/ug.
Applications: E, WB
Application Notes:
The activity is determined by the ability to induce proliferation of TF-1 cells and is typically less than 0.20 ng/mL. Specific activity: 5 x 10e6 units/mg
Accession No.: P13725
MW: 23800 Da
Sequence:
MAAIGSCSKE YRVLLGQLQK QTDLMQDTSR LLDPYIRIQG LDVPKLREHC RERPGAFPSE ETLRGLGRRG FLQTLNATLG CVLHRLADLE QRLPKAQDLE RSGLNIEDLE KLQMARPNIL GLRNNIYCMA QLLDNSDTAE PTKAGRGASQ PPTPTPASDA FQRKLEGCRF LHGYHRFMHS VGRVFSKWGE SPNRSRRHSP HQALRKGVRR
Purity:
Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
Format:
Each vial contains 10 ug of lyophilized protein. Reconstitute with 0.1 ml sterile deionized water for a final concentration of 0.1 mg/ml.
Storage: Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
Pathway and Disease: Cell Growth and Death, Signal Transduction, Signaling Molecules and Interaction
Alternate Names: Onc-M, Oncostatin M, OSMDescription:
Oncostatin M (OSM) is a growth regulator produced by a variety of cells and has a wide range of attributed functions. Several of these functions include: inhibition of tumor cell line proliferation, liver development/regeneration, regulation of cytokine production (hematopoiesis and inflammation), bone development and possibly nervous system development. Human OSM is produced in E. coli as a non-glycosylated protein, containing 210 amino acids, with a molecular weight of 23.8 kDa.
Source: E. coli. Endotoxin level as measured by LAL is <0.05ng/ug or <0.5EU/ug.
Applications: E, WB
Application Notes:
The activity is determined by the ability to induce proliferation of TF-1 cells and is typically less than 0.20 ng/mL. Specific activity: 5 x 10e6 units/mg
Accession No.: P13725
MW: 23800 Da
Sequence:
MAAIGSCSKE YRVLLGQLQK QTDLMQDTSR LLDPYIRIQG LDVPKLREHC RERPGAFPSE ETLRGLGRRG FLQTLNATLG CVLHRLADLE QRLPKAQDLE RSGLNIEDLE KLQMARPNIL GLRNNIYCMA QLLDNSDTAE PTKAGRGASQ PPTPTPASDA FQRKLEGCRF LHGYHRFMHS VGRVFSKWGE SPNRSRRHSP HQALRKGVRR
Purity:
Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
Format:
Each vial contains 10 ug of lyophilized protein. Reconstitute with 0.1 ml sterile deionized water for a final concentration of 0.1 mg/ml.
Storage: Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
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