OSMR Polyclonal Antibody

Background:
This gene encodes a member of the type I cytokine receptor family. The encoded protein heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events. Mutations in this gene have been associated with familial primary localized cutaneous amyloidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Research Area: Immunology,Signal Transduction,Epigenetics and Nuclear Signaling

Synonyms:
OSMR, IL-31R-beta, IL-31RB, OSMRB, PLCA1

Immunogen: Recombinant fusion protein of human OSMR (NP_003990.1).

Swissprot: Q99650
Gene ID: 9180

Calculated MW: 39 kDa/110 kDa
Observed MW: 111 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.