Osteopontin polyclonal, anti-human

Protein Family: CAM Ligands

Pathway and Disease: Cell Communication, Immune System, Signaling Molecules and Interaction

Description:
Osteopontin (OPN) binds tightly to hydroxyapatite and forms an integral part of the bone mineralized matrix. OPN is an integrin alpha-V/beta-3 ligand indicating a role in cell-matrix interaction. OPN is essential in the type I immunity pathway by increasing IFN-gamma and IL-12 production. OPN acts as the stone matrix in urinary stone formation.

Alternate Names: Osteopontin, bone sialoprotein 1, secreted phosphoprotein 1, SPP-1, urinary stone protein, nephropontin, uropontin, SPP1, BNSP, OPN

Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500

Accession No.: P10451

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human OPN.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.