OTC Rabbit polyclonal antibody, anti-human, mouse, rat

Background:
This nuclear gene encodes a mitochondrial matrix enzyme. Missense| nonsense| and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency| which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy| it may play a role in that disease also.

Research Area: Metabolism, Signal transduction, Tags & cell markers

Synonyms: OTC, Ornithine carbamoyltransferase, mitochondrial, EC 2.1.3.3, Ornithine transcarbamylase, OTCase

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year