Otocadherin Polyclonal Antibody

Background:
This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Alternative splice variants encoding different isoforms have been described.

Research Area: Neuroscience, Signal Transduction

Synonyms:
Age related hearing loss 1, Ahl 1, Ahl, Ahl1, Bob, Bobby, Bus, Bustling, Cadherin 23, Cadherin23, CDH 23, Mdfw, Modifier of deaf waddler, nmf112, nmf181, nmf252, Otocadherin, USH 1D, USH1 D, USH1D, Waltzer

Immunogen: Recombinant protein of human CDH23

Swissprot: Q9H251
Gene Accession: BC139903

Calculated MW: 45 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-26338/sc-32864