OTUB1 antibody (clone 1C12), anti-human
€435.00
In stock
SKU
AC-AT3158a
Catalog Number: AC-AT3158a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
Request Information AC-AT3158a">Request Information
Background:
The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants.
Other Names:
Ubiquitin thioesterase OTUB1, Deubiquitinating enzyme OTUB1, OTU domain-containing ubiquitin aldehyde-binding protein 1, Otubain-1, hOTU1, Ubiquitin-specific-processing protease OTUB1, OTUB1, OTB1, OTU1
Antigen Type:
Recombinant Protein
Gene Name: OTUB1
Gene ID: 55611
NCBI Accession: NP_060140.2
Primary Accession: Q96FW1
Other Accession: BC007519
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants.
Other Names:
Ubiquitin thioesterase OTUB1, Deubiquitinating enzyme OTUB1, OTU domain-containing ubiquitin aldehyde-binding protein 1, Otubain-1, hOTU1, Ubiquitin-specific-processing protease OTUB1, OTUB1, OTB1, OTU1
Antigen Type:
Recombinant Protein
Gene Name: OTUB1
Gene ID: 55611
NCBI Accession: NP_060140.2
Primary Accession: Q96FW1
Other Accession: BC007519
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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