OVOL2 Polyclonal Antibody

Background:
This gene encodes a member of the evolutionarily conserved ovo-like protein family. Mammalian members of this family contain a single zinc finger domain composed of a tetrad of C2H2 zinc fingers with variable N- and C-terminal extensions that contain intrinsically disordered domains. Members of this family are involved in epithelial development and differentiation. Knockout of this gene in mouse results in early embryonic lethality with phenotypes that include neurectoderm expansion, impaired vascularization, and heart anomalies. In humans, allelic variants of this gene have been associated with posterior polymorphous corneal dystrophy.

Research Area: Epigenetics and Nuclear Signaling, Developmental biology, Stem cells

Synonyms:
bA504H3.3, EUROIMAGE566589, hOvo 2, hOvo2, Ovo like 2 (Drosophila), Ovo like 2, ovo-like zinc finger 2, OVOL 2, OVOL2, OVOL2, Transcription factor Ovo like 2, Transcription factor Ovo-like 2, Zinc finger protein 339, ZNF 339, ZNF339

Immunogen: Fusion protein of human OVOL2

Swissprot: Q9BRP0
Gene Accession: BC006148

Calculated MW: 30 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.84 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.