P cadherin polyclonal, anti-human

Quantity: 100 µg

Background:
Cadherins, such as CDH3, are integral membrane glycoproteins responsible for calcium-dependent cell-cell adhesion. Cadherin-3 is a protein that in humans is encoded by the CDH3 gene. This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.

Description:
Rabbit IgG polyclonal antibody for Cadherin-3 (CDH3) detection. Tested with WB, IHC-P, ICC in Human.

Synonyms:
CADH3_HUMAN antibody, Cadherin 3 antibody, Cadherin 3 precursor antibody, Cadherin 3 type 1 antibody, Cadherin-3 antibody, Cadherin-3 precursor antibody, Cadp antibody, Calcium dependent adhesion protein placental antibody, Calcium-dependent adhesion protein placental antibody, CDH 3 antibody, CDH3 antibody, CDH3 protein antibody, CDHP antibody, HJMD antibody, P cadherin(placental) antibody, P-cadherin(placental) antibody, P-cadherin antibody, PCAD antibody, Placental cadherin antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human P cadherin(612-626aa QDTYDVHLSLSDHGN), different from the mouse and rat sequences by one amino acid.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, IHC-P, ICC

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.