P-glycoprotein polyclonal, anti-human, mouse, rat antibody
€1,125.00
In stock
SKU
AC-ABV11487-100
Catalog Number: AC-ABV11487-100
Size: 100 µg
Host: Rabbit IgG
Applications: IHC, IHC-F
Datasheet
Request Information
Size: 100 µg
Host: Rabbit IgG
Applications: IHC, IHC-F
Datasheet
Request Information
Background:
P-gp, also called MDR1 or ABCB1, is a glycoprotein that in humans is encoded by the ABCB1 gene. P-gp is a well-characterized ABC-transporter (which transports a wide variety of xenobiotics across extra- and intracellular membranes). It is an ATP-dependent drug efflux pump with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein functions in the kidneys, liver, blood–brain barrier and the intestinal epithelium.
Other Names:
P-gp, Multidrug resistance protein 1, MDR1, ATP-binding cassette sub-family B (MDR/TAP) member 1, ABCB1
Primary Accession: P08183
Gene Name: ABCB1 (HGNC:40)
Gene ID: 5243
P-gp, also called MDR1 or ABCB1, is a glycoprotein that in humans is encoded by the ABCB1 gene. P-gp is a well-characterized ABC-transporter (which transports a wide variety of xenobiotics across extra- and intracellular membranes). It is an ATP-dependent drug efflux pump with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein functions in the kidneys, liver, blood–brain barrier and the intestinal epithelium.
Other Names:
P-gp, Multidrug resistance protein 1, MDR1, ATP-binding cassette sub-family B (MDR/TAP) member 1, ABCB1
Primary Accession: P08183
Gene Name: ABCB1 (HGNC:40)
Gene ID: 5243
| Is Featured? | No |
|---|
Write Your Own Review