p16INK4a/CDKN2 (clone DCS-50), anti-human
€455.00
In stock
SKU
AC-ABO10459
Catalog Number: AC-ABO10459
Size: 100 µg
Isotype: Mouse IgG
Applications: WB, IHC-F, ICC
Datasheet
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Size: 100 µg
Isotype: Mouse IgG
Applications: WB, IHC-F, ICC
Datasheet
Request Information
Description: Mouse IgG monoclonal antibody for p16INK4a/CDKN2, cyclin-dependent kinase inhibitor 2A (CDKN2A) detection. Tested with WB, IHC-F, ICC in Human. No cross reactivity with other proteins.Protein Name: Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3
Protein Function:
Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein (By similarity). .
Other Names: Cyclin-dependent kinase inhibitor 2A {ECO:0000312|RGD:2323}, Cyclin-dependent kinase 4 inhibitor A, CDK4I, p16-INK4a, p16, p16-INK4, Cdkn2a {ECO:0000312|EMBL:AAL76338.1, ECO:0000312|RGD:2323}
Clone Name(s):
DCS-50
Subcellular Localization: Cytoplasm . Nucleus .
Tissue Specificity: Expressed in spleen, liver and lung. Not detected in kidney, colon, stomach or brain. .
Gene ID: 25163
Immunogen: Recombinant human p16 protein.
Calculated MW: 17366
Purification: Ascites
Format: Lyophilized
Reconstitution: Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Contents: Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
Concentration (mg/ml): Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Protein Function:
Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein (By similarity). .
Other Names: Cyclin-dependent kinase inhibitor 2A {ECO:0000312|RGD:2323}, Cyclin-dependent kinase 4 inhibitor A, CDK4I, p16-INK4a, p16, p16-INK4, Cdkn2a {ECO:0000312|EMBL:AAL76338.1, ECO:0000312|RGD:2323}
Clone Name(s):
DCS-50
Subcellular Localization: Cytoplasm . Nucleus .
Tissue Specificity: Expressed in spleen, liver and lung. Not detected in kidney, colon, stomach or brain. .
Gene ID: 25163
Immunogen: Recombinant human p16 protein.
Calculated MW: 17366
Purification: Ascites
Format: Lyophilized
Reconstitution: Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Contents: Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
Concentration (mg/ml): Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
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