P23 Polyclonal Antibody

Background:
Prostaglandin E synthase 3 (cytosolic)is anenzymethat in humans is encoded by the PTGES3gene. The protein encoded by this gene is also known as p23 which functions as a chaperone which is required for proper functioning of the glucocorticoid and other steroid receptors. Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction

Synonyms:
Co chaperone p23, cPGES, Cytosolic prostaglandin E synthase, Cytosolic prostaglandin E2 synthase, Hsp90 co chaperone, Hsp90 co-chaperone, P23, Progesterone receptor complex, Progesterone receptor complex p23, Prostaglandin E synthase 3 (cytosolic), Prostaglandin E synthase 3, PTGES 3, PTGES3, Sid 3177, TEBP, TEBP, Telomerase binding protein p23, Telomerase-binding protein p23, Unactive progesterone receptor 23 kD

Immunogen: Recombinant protein of human PTGES3

Swissprot: Q15185
Gene Accession: BC003005

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-66254/sc-66256/sc-68399