P27 KIP 1 polyclonal, anti-rat, human

Quantity: 100 µg

Background:
Cyclin-dependent kinase inhibitor 1B (p27KIP1), also known as KIP1 or P27, is an enzyme inhibitor that in humans is encoded by the CDKN1B gene. It encodes a protein which belongs to the Cip/Kipfamily of cyclin dependent kinase (Cdk) inhibitor proteins. It is mapped to 12p13.1. p27KIP1 can inhibit both CDK activation and the kinase activity of assembled and activated cyclin-CDK. The function of p27KIP1 is associated with an aggressive phenotype in human breast cancer. Downregulation of p27KIP1 by CK2-alpha-prime is necessary for development of agonist- and stress-induced cardiac hypertrophy.

Description:
Rabbit IgG polyclonal antibody for Cyclin-dependent kinase inhibitor 1B (CDKN1B) detection. Tested with WB in Humnan, Rat.

Synonyms:
AA408329 antibody, AI843786 antibody, Cdki1b antibody, CDKN 1B antibody, CDKN 4 antibody, CDKN1B antibody, CDKN4 antibody, CDN1B_HUMAN antibody, Cyclin Dependent Kinase Inhibitor 1B antibody, Cyclin dependent kinase inhibitor p27 antibody, Cyclin-dependent kinase inhibitor 1B (p27, Kip1) antibody, Cyclin-dependent kinase inhibitor 1B antibody, Cyclin-dependent kinase inhibitor p27 antibody, Cyclin-dependent kinase inhibitor p27 Kip1 antibody, KIP 1 antibody, KIP1 antibody, MEN1B antibody, MEN4 antibody, OTTHUMP00000195098 antibody, OTTHUMP00000195099 antibody, p27 antibody, p27 Kip1 antibody, P27-like cyclin-dependent kinase inhibitor antibody, P27KIP1 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human P27 KIP 1 recombinant protein (Position: S10-T198). Human P27 KIP 1 shares 87% amino acid (aa) sequence identity with mouse P27 KIP 1.E.coli-derived human P27 KIP 1 recombinant protein (Position: S10-T198). Human P27 KIP 1 shares 87% amino acid (aa) sequence identity with mouse P27 KIP 1.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: rat.
Predicted to work with: human.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.