p27Kip1 (Mitotic Inhibitor/Suppressor Protein) (clone DCS-72.F6 + KIP1/769 ), anti-human, mouse, rat, primate

Background:
Recognizes a 27kDa protein, identified as the p27Kip1, a cell cycle regulatory mitotic inhibitor. Its epitope spans between aa 83-204 of p27. It is highly specific and shows no cross-reaction with other related mitotic inhibitors. p27Kip1 functions as a negative regulator of G1 progression and has been proposed to function as a possible mediator of TGF- induced G1 arrest. p27Kip1 is a candidate tumor suppressor gene. This MAb co-precipitates cdk4 in complex p27Kip1 and is excellent for staining of formalin-fixed tissues.

Other Names:
Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, p27Kip1, CDKN1B, KIP1

Gene Name: CDKN1B {ECO:0000303|PubMed:20824794}
Gene ID: 1027
Primary Accession: P46527
Other Accession: 1027, 238990