P2RX3 Polyclonal Antibody

Background:
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage.

Research Area: Cancer, Metabolism, Neuroscience

Synonyms:
ATP receptor, MGC129956, P2rx3, P2RX3, P2X purinoceptor 3, P2X receptor subunit 3, P2X3, Purinergic receptor, Purinergic receptor P2X ligand gated ion channel 3, Purinergic receptor P2X3, Purinoceptor P2X3

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse P2X3

Swissprot: Q3UR32,P49654

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Concentration: 420 μg/mL
Dilution: IHC 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.