P2RX7 / P2X7 receptor polyclonal, anti-human

Background:
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria.

Other Names:
P2X purinoceptor 7, P2X7, ATP receptor, P2Z receptor, Purinergic receptor, P2RX7

Antigen Types:
Synthetic Peptide

Gene Name:
P2RX7
Gene ID:
5027
Primary Accession: Q99572
Other Accession: NP_002553;5027;18439 (mouse); 29665 (rat);