P2RX7 polyclonal, anti-human, mouse, rat

Background:
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria.

Synonyms: P2X7

Cellular Location: Cell membrane Multi-pass membrane protein

Immunogen:
Recombinant protein of human P2RX7

Gene Symbol: P2RX7

Gene ID: 5027

Swiss prot: Q99572

Calculated MW: 69kDa

Recommended dilution:
WB 1:1000-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.