P2RY1 Polyclonal Antibody

Background:
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.

Research Area: Cancer, Neuroscience, Signal Transduction

Synonyms:
ATP receptor, P2 purinoceptor subtype Y1, P2RY1, P2RY1, P2Y purinoceptor 1, P2Y1, P2Y1 purinoceptor, Platelet ADP receptor, Purinergic receptor, Purinergic receptor P2Y G protein coupled 1, Purinergic receptor P2Y1

Immunogen: Synthetic peptide of human P2RY1

Swissprot: P47900
Gene Accession: NP_002554

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: IHC 1:25-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-15204/sc-20123