P2RY11 Polyclonal Antibody

Background:
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is coupled to the stimulation of the phosphoinositide and adenylyl cyclase pathways and behaves as a selective purinoceptor. Naturally occuring read-through transcripts, resulting from intergenic splicing between this gene and an immediately upstream gene (PPAN, encoding peter pan homolog), have been found. The PPAN-P2RY11 read-through mRNA is ubiquitously expressed and encodes a fusion protein that shares identity with each individual gene product.

Research Area: Neuroscience

Synonyms:
P2RY11, P2Y purinoceptor 11, P2Y11, P2Y11 receptor, P2Y11, Purinergic receptor P2Y G protein coupled 11, Purinergic receptor P2Y11

Immunogen: Synthetic peptide of human P2RY11

Swissprot: Q96G91
Gene Accession: NP002557

Calculated MW: 40 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.6 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:500-1000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.