P2X2 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
The P2RX2 gene encodes the P2X2 receptor, which assembles as a trimer to form a ligand-gated ion channel gated by extracellular ATP. P2X2 receptors mediate a variety of cellular responses, including excitatory postsynaptic responses in sensory neurons. The product of this gene belongs to the family of purinoceptors for ATP. P2RX2 is mapped to 12q24.33. It has been found that ATP-activated P2RX2 influenced OHC electromotility, a stimulus-induced change in hair cell length that functions as an amplifier to determine hearing sensitivity and frequency selectivity. What’s more, P2RX2 channels were necessary for development of the temporary threshold shift.

Description:
Rabbit IgG polyclonal antibody for P2X purinoceptor 2 (P2RX2) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
ATP receptor antibody, MGC129601 antibody, P2RX 2 antibody, P2RX2 antibody, P2RX2_HUMAN antibody, P2X purinoceptor 2 antibody, P2X Receptor subunit 2 antibody, P2X2 antibody, P2X2a antibody, Purinergic receptor antibody, Purinergic receptor P2X ligand gated ion channel 2 antibody, Purinergic receptor P2X2 isoform A antibody, Purinergic receptor P2X2 isoform B antibody, Purinergic receptor P2X2 isoform C antibody, Purinergic receptor P2X2 isoform D antibody, Purinergic receptor P2X2 isoform H antibody, Purinergic receptor P2X2 isoform I antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human P2X2 recombinant protein (Position: D139-L471). Human P2X2 shares 84% amino acid (aa) sequence identity with both mouse and rat P2X2.E.coli-derived human P2X2 recombinant protein (Position: D139-L471). Human P2X2 shares 84% amino acid (aa) sequence identity with both mouse and rat P2X2.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.