P2X3 polyclonal, anti-human

Background:
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage.

Synonyms: P2RX3, ATP receptor, MGC129956, Purinergic receptor

Cellular Location: Nucleus Cytoplasm

Immunogen:
A synthetic peptide of human P2X3

Gene Symbol: P2X3

Gene ID: 5024

Swiss prot: P56373

Calculated MW: 44kDa

Recommended dilution:
IHC 1:25-100

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.