P311 Polyclonal Antibody
€0.00
In stock
SKU
ELK-ES8018
Catalog Number: ELK-ES8018
Reactivity: Human, Mouse, Rat
Applications: IHC-p, ELISA
Information
Request Manual ELK-
Questions? Contact us!
Reactivity: Human, Mouse, Rat
Applications: IHC-p, ELISA
Information
Request Manual ELK-
Questions? Contact us!
Background:
P311, also known as C5orf13 (chromosome 5 open reading frame 13), D4S114, PTZ17 or PRO1873, is a 68 amino acid cytoplasmic protein involved in cellular differentiation, neural function and axonal regeneration. Found in the granular layer of the cerebellum, P311 is expressed at lower levels in hippocampus, olfactory bulb, kidney, liver and heart and when expressed ectopically, P311 augments giloma motility. P311 is enriched in mice within the superficial cortical layers and striatum at E20 and the germinal zones at E17. Known to interact with Filamin 1, P311 regulates retinoic-acid lipid-droplet biogenesis, induces myofibroblast ameboid migration and the differentiation of fibroblasts into myofibroblasts. Ser-59 phosphorylation decreases P311 stability; the gene encoding P311 maps to human chromosome 5q22.
Alternative Names:
NREP, C5orf13, P311, Neuronal regeneration-related protein, Neuronal protein 3.1, Protein p311
Immunogen: The antiserum was produced against synthesized peptide derived from human C5orf13. AA range:13-62
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
GeneID: NREP
Storage: -20°C/1 year
NOTE: For Research Use Only
P311, also known as C5orf13 (chromosome 5 open reading frame 13), D4S114, PTZ17 or PRO1873, is a 68 amino acid cytoplasmic protein involved in cellular differentiation, neural function and axonal regeneration. Found in the granular layer of the cerebellum, P311 is expressed at lower levels in hippocampus, olfactory bulb, kidney, liver and heart and when expressed ectopically, P311 augments giloma motility. P311 is enriched in mice within the superficial cortical layers and striatum at E20 and the germinal zones at E17. Known to interact with Filamin 1, P311 regulates retinoic-acid lipid-droplet biogenesis, induces myofibroblast ameboid migration and the differentiation of fibroblasts into myofibroblasts. Ser-59 phosphorylation decreases P311 stability; the gene encoding P311 maps to human chromosome 5q22.
Alternative Names:
NREP, C5orf13, P311, Neuronal regeneration-related protein, Neuronal protein 3.1, Protein p311
Immunogen: The antiserum was produced against synthesized peptide derived from human C5orf13. AA range:13-62
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
GeneID: NREP
Storage: -20°C/1 year
NOTE: For Research Use Only
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