p40 (deltaNp63) (Squamous, Basal & Myoepithelial Cell Marker) polyclonal, anti-human, mouse, rat, bovine
€0.00
In stock
SKU
AC-AH10824
Catalog Number: AC-AH10824
Size: 20 µg, 100 µg
Isotype: Rabbit
Clone Name:
Applications: WB, IHC-P, IF, FC
Datasheet
Request Information
Size: 20 µg, 100 µg
Isotype: Rabbit
Clone Name:
Applications: WB, IHC-P, IF, FC
Datasheet
Request Information
Background:
p40 (p63 delta) is a marker recently determined to be highly specific for squamous basal cells in the immunohistochemistry (IHC) application. The current more routinely recommended marker, p63, appears to have less specificity compared to p40, especially on squamous cell tumors. The ability to differentiate between lung adenocarcinoma vs. squamous cell carcinoma is difficult and has bearing on the different therapeutic avenues for each subtype treatment. p63 antibodyā€™s ability to distinguish between the tumor types appears to be inferior when compared to p40. The ability to utilize an antibody probe for p40 as a squamous cell marker bolsters its use for future sub-classification of lung cancers, especially by immunohistochemical techniques.
Other Names:
Tumor protein 63, p63, Chronic ulcerative stomatitis protein, CUSP, Keratinocyte transcription factor KET, Transformation-related protein 63, TP63, Tumor protein p73-like, p73L, p40, p51, TP63, KET, P63, P73H, P73L, TP73L
Gene Name: TP63
Gene ID: 8626
Primary Accession: Q9H3D4
Other Accession: 8626, 137569
p40 (p63 delta) is a marker recently determined to be highly specific for squamous basal cells in the immunohistochemistry (IHC) application. The current more routinely recommended marker, p63, appears to have less specificity compared to p40, especially on squamous cell tumors. The ability to differentiate between lung adenocarcinoma vs. squamous cell carcinoma is difficult and has bearing on the different therapeutic avenues for each subtype treatment. p63 antibodyā€™s ability to distinguish between the tumor types appears to be inferior when compared to p40. The ability to utilize an antibody probe for p40 as a squamous cell marker bolsters its use for future sub-classification of lung cancers, especially by immunohistochemical techniques.
Other Names:
Tumor protein 63, p63, Chronic ulcerative stomatitis protein, CUSP, Keratinocyte transcription factor KET, Transformation-related protein 63, TP63, Tumor protein p73-like, p73L, p40, p51, TP63, KET, P63, P73H, P73L, TP73L
Gene Name: TP63
Gene ID: 8626
Primary Accession: Q9H3D4
Other Accession: 8626, 137569
| Is Featured? | No |
|---|
Write Your Own Review