p44/42 MAPK (Erk1/2) polyclonal, anti-human, mouse, rat, chicken, sheep antibody
€285.00
In stock
SKU
AC-ABV10062-100
Catalog Number: AC-ABV10062-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
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Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
Request Information
Background:
The extracellular signal-regulated kinase 1 and 2 (Erk1 and Erk2) are closely related mitogen activated protein (MAP) kinases that are activated thro µgh the extracellular stimulation by many growth factors, mitogens and differentiation promoting agents via a protein kinase cascade. Erk1/2 are activated approximately 1000 fold by phosphorylation of neighboring threonine and tyrosine residues by Mek1 and Mek2. Both sites must be phosphorylated for maximum activity. Erk1/2 kinases are ubiquitously distributed in the nervous system, as well as a broad range of cells and tissues. These two kinases represent proximal kinases in the classical MAP kinase cascade pathway which links growth and differentiation signals at the cell surface (thro µgh tyrosine kinase) with transcription in the nucleus.
Other Names:
MAPK1, p38, ERK , P42MAPK, ERK2 , p40 , PRKM1 , p41mapk , PRKM2, MAPK2 , p42-MAPK, p41 , ERK-2, ERT1
Primary Accession: P63086
Gene Name: Mapk1
Gene ID: 116590
Concentration (mg/ml): 0.5 mg/ml
The extracellular signal-regulated kinase 1 and 2 (Erk1 and Erk2) are closely related mitogen activated protein (MAP) kinases that are activated thro µgh the extracellular stimulation by many growth factors, mitogens and differentiation promoting agents via a protein kinase cascade. Erk1/2 are activated approximately 1000 fold by phosphorylation of neighboring threonine and tyrosine residues by Mek1 and Mek2. Both sites must be phosphorylated for maximum activity. Erk1/2 kinases are ubiquitously distributed in the nervous system, as well as a broad range of cells and tissues. These two kinases represent proximal kinases in the classical MAP kinase cascade pathway which links growth and differentiation signals at the cell surface (thro µgh tyrosine kinase) with transcription in the nucleus.
Other Names:
MAPK1, p38, ERK , P42MAPK, ERK2 , p40 , PRKM1 , p41mapk , PRKM2, MAPK2 , p42-MAPK, p41 , ERK-2, ERT1
Primary Accession: P63086
Gene Name: Mapk1
Gene ID: 116590
Concentration (mg/ml): 0.5 mg/ml
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