p44-MAPK polyclonal, anti-human, mouse, rat

Protein Family: Enzymes, Protein Kinases

Pathway and Disease: Signal Transduction, Cell Motility, Cell Growth and Death, Cell Communication, Immune System, Cancers, Endocrine System, Development and Behavior, Nervous and Sensory Systems, Metabolic Disorders, Infectious Diseases

Description:
MAP kinase isoform (p44-MAPK) is involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1 and EIF4EBP1. p44-MAPK is required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2).

Alternate Names: MAPK 1, ERK-1, Mitogen-activated protein kinase 3, Extracellular signal-regulated kinase 1, Insulin-stimulated MAP2 kinase, MAP kinase 1, p44-ERK1, ERT2, P44-MAPK, Microtubule-associated protein 2 kinase, MAPK3, ERK1, PRKM3

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; IP: 1:100-1:500

Accession No.: P27361

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human p44-MAPK.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.