P450R Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP6518a
Background:
P450R is an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in its gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.
Other Names:
NADPH--cytochrome P450 reductase, CPR, P450R, POR, CYPOR
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6518a was selected from the N-term region of human P450R. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: POR {ECO:0000255|HAMAP-Rule:MF_03212}
Gene ID: 5447
Primary Accession: P16435
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
P450R is an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in its gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.
Other Names:
NADPH--cytochrome P450 reductase, CPR, P450R, POR, CYPOR
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6518a was selected from the N-term region of human P450R. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: POR {ECO:0000255|HAMAP-Rule:MF_03212}
Gene ID: 5447
Primary Accession: P16435
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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