P450R polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP6518C
Catalog Number: AC-AP6518C
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB19543
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB19543
Applications: IHC-P, WB
Datasheet
Request Information
Background:
P450R is an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in its gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.
Other Names:
NADPH--cytochrome P450 reductase, CPR, P450R, POR, CYPOR
Target/Specificity:
This P450R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 462-488 amino acids from the Central region of human P450R.
Antigen Region:
462-488
Antigen Type: Synthetic Peptide
Gene Name: POR {ECO:0000255|HAMAP-Rule:MF_03212}
Gene ID: 5447
Primary Accession: P16435
NCBI Accession: NP_000932.3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
P450R is an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in its gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.
Other Names:
NADPH--cytochrome P450 reductase, CPR, P450R, POR, CYPOR
Target/Specificity:
This P450R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 462-488 amino acids from the Central region of human P450R.
Antigen Region:
462-488
Antigen Type: Synthetic Peptide
Gene Name: POR {ECO:0000255|HAMAP-Rule:MF_03212}
Gene ID: 5447
Primary Accession: P16435
NCBI Accession: NP_000932.3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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