p47-phox polyclonal, anti-mouse, rat
€469.00
In stock
SKU
252159
Catalog Nr.: 252159
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC, IF
Datasheet
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Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC, IF
Datasheet
Request Information
Protein Family: Transporters
Pathway and Disease: Infectious Diseases; Immune System
Description:
p47-phox (NCF1) interacts with NCF2 and cytochrome b558 for activation of NADPH oxidase, which is required for superoxide production. Defects in p47-phox are linked to chronic granulomatous disease, a genetic disorder characterized by the inability of neutrophils and phagocytes to kill microbes they have ingested. Patients can suffer from life-threatening bacterial or fungal infections.
Alternate Names: Neutrophil cytosol factor 1, NCF-1, Neutrophil NADPH oxidase factor 1, 47 kDa neutrophil oxidase factor, p47-phox, NCF-47K, 47 kDa autosomal chronic granulomatous disease protein, Nox-organizing protein 2, Nox organizer 2, SH3 and PX domain-containing protein 1A, NCF1, NOXO2, SH3PXD1A
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; IF: 1:100-1:500
Accession No.: Q09014
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of mouse p47-phox.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 1% BSA with 0.09% sodium azide. Antibody was purified by immunogen-affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Kim J et al. 2013. PLoS ONE. 8(9):e74458. PMID# 24040253
Pathway and Disease: Infectious Diseases; Immune System
Description:
p47-phox (NCF1) interacts with NCF2 and cytochrome b558 for activation of NADPH oxidase, which is required for superoxide production. Defects in p47-phox are linked to chronic granulomatous disease, a genetic disorder characterized by the inability of neutrophils and phagocytes to kill microbes they have ingested. Patients can suffer from life-threatening bacterial or fungal infections.
Alternate Names: Neutrophil cytosol factor 1, NCF-1, Neutrophil NADPH oxidase factor 1, 47 kDa neutrophil oxidase factor, p47-phox, NCF-47K, 47 kDa autosomal chronic granulomatous disease protein, Nox-organizing protein 2, Nox organizer 2, SH3 and PX domain-containing protein 1A, NCF1, NOXO2, SH3PXD1A
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; IF: 1:100-1:500
Accession No.: Q09014
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of mouse p47-phox.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 1% BSA with 0.09% sodium azide. Antibody was purified by immunogen-affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Kim J et al. 2013. PLoS ONE. 8(9):e74458. PMID# 24040253
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