p53 (clone ), anti-human

Protein Family: Transcription Factors

Pathway and Disease: Cancers, Cell Communication, Cell Growth and Death, Folding, Sorting and Degradation, Signal Transduction

Description:
p53 acts as a tumor suppressor in many tumor types by inducing growth arrest or apoptosis. P53 is also involved in cell cycle regulation as transactivator that negatively regulate cell division. Defects in p53 are the cause of numerous cancers.

Alternate Names: Cellular tumor antigen p53, Tumor suppressor p53, phosphoprotein p53, Antigen NY-CO-13, TP53

Application Notes: Purified antibody is suitable for immunohistochemistry with acetone or formalin-fixed frozen and paraffin-embedded tissues. E: 1:10,000-1:50,000; WB: 1:1,000-1:2,000; IHC: 1:500-1:2,000

Accession No.: P04637

Antigen: KLH-conjugated human wild-type p53 protein.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.2% BSA with 0.09% sodium azide. Antibody was purified by anti-mouse IgG affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.