P53 (clone N33), anti-human
€0.00
In stock
SKU
BMA1033
Catalog Number: BMA1033
Size: 100 μg
Isotype: Mouse IgG2b
Reactivity: human
Application(s): WB, IHC-P, ICC, Flow-Cyt
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Size: 100 μg
Isotype: Mouse IgG2b
Reactivity: human
Application(s): WB, IHC-P, ICC, Flow-Cyt
Request Information
Background:
P53 (also known as protein 53 or tumor protein 53), is a 393-amino acid protein, and its molecular weight is about 53KDa. It is crucial in multicellular organisms, where it regulates the cell cycle and, thus, functions as a tumor suppressor that is involved in preventing cancer. As such, P53 has been described as "the guardian of the genome" because of its role in conserving stability by preventing genome mutation. It is an important key element which controls cell cycle progression in response to cellular stress like DNA damage. Its ability to act as transcriptional activator or repressor links transcription and cell cycle control.
Immunogen:
Recombinanthuman P53 protein.
Recommended Application:
Western Blot, WB(1:500); Immunohistochemistry, IHC-P (1:50-100); Immunocytochemistry, ICC (1:50-100); Flow Cytometry, Flow-Cyt (1:50-100)
Product Form: Liquid
Purification: Protein A purified
Storage Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol and 0.05% Sodium Azide.
Storage Instruction:
Store at 4℃ after thawing (1 week). Aliquot and store at -20℃ for long term (at least one year). Avoid repeated freeze and thaw cycles.
P53 (also known as protein 53 or tumor protein 53), is a 393-amino acid protein, and its molecular weight is about 53KDa. It is crucial in multicellular organisms, where it regulates the cell cycle and, thus, functions as a tumor suppressor that is involved in preventing cancer. As such, P53 has been described as "the guardian of the genome" because of its role in conserving stability by preventing genome mutation. It is an important key element which controls cell cycle progression in response to cellular stress like DNA damage. Its ability to act as transcriptional activator or repressor links transcription and cell cycle control.
Immunogen:
Recombinanthuman P53 protein.
Recommended Application:
Western Blot, WB(1:500); Immunohistochemistry, IHC-P (1:50-100); Immunocytochemistry, ICC (1:50-100); Flow Cytometry, Flow-Cyt (1:50-100)
Product Form: Liquid
Purification: Protein A purified
Storage Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol and 0.05% Sodium Azide.
Storage Instruction:
Store at 4℃ after thawing (1 week). Aliquot and store at -20℃ for long term (at least one year). Avoid repeated freeze and thaw cycles.
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