p57 (phospho Thr310) Polyclonal Antibody

p57 (phospho Thr310) Polyclonal Antibody

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In stock
SKU
ELK-ES4453
Catalog Number: ELK-ES4453
Reactivity: Human, Mouse
Applications: WB, IHC-p, IF, ELISA
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Background:
cyclin dependent kinase inhibitor 1C(CDKN1C) Homo sapiens This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010],

Alternative Names:
CDKN1C, KIP2, Cyclin-dependent kinase inhibitor 1C, Cyclin-dependent kinase inhibitor p57, p57Kip2

Immunogen: The antiserum was produced against synthesized peptide derived from human p57 Kip2 around the phosphorylation site of Thr310. AA range:267-316

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 32

GeneID: CDKN1C

Storage: -20°C/1 year

NOTE: For Research Use Only
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