p73 monoclonal, anti-human, mouse, rat

p73 monoclonal, anti-human, mouse, rat

€455.00
In stock
SKU
AC-ABO13253
Catalog Number: AC-ABO13253
Size: 100 µl
Isotype: Rabbit IgG
Applications: WB, IHC, IF, ICC
Datasheet
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Description: Anti-p73 Rabbit Monoclonal Antibody . Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Protein Function:
Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein..

Other Names: Tumor protein p73, p53-like transcription factor, p53-related protein, TP73, P73

Clone Name(s):
Clone: EHI-20

Subcellular Localization: Nucleus. Cytoplasm. Accumulates in the nucleus in response to DNA damage.

Tissue Specificity: Expressed in striatal neurons of patients with Huntington disease (at protein level). Brain, kidney, placenta, colon, heart, liver, spleen, skeletal muscle, prostate, thymus and pancreas. Highly expressed in fetal tissue..

Gene ID: 7161

Immunogen: A synthesized peptide derived from human p73

Calculated MW: 69623

Purification: Affinity-chromatography

Format: Liquid

Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Concentration (mg/ml): Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Storage: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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