PA26 Polyclonal Antibody
€0.00
In stock
SKU
ELK-ES5548
Catalog Number: ELK-ES5548
Reactivity: Human, Mouse, Rat
Applications: WB, IHC-p, ELISA
Information
Request Manual ELK-
Questions? Contact us!
Reactivity: Human, Mouse, Rat
Applications: WB, IHC-p, ELISA
Information
Request Manual ELK-
Questions? Contact us!
Background:
sestrin 1(SESN1) Homo sapiens This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010],
Alternative Names:
SESN1, PA26, SEST1, Sestrin-1, p53-regulated protein PA26
Immunogen: The antiserum was produced against synthesized peptide derived from human SESN1. AA range:271-320
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 57
GeneID: SESN1
Storage: -20°C/1 year
NOTE: For Research Use Only
sestrin 1(SESN1) Homo sapiens This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010],
Alternative Names:
SESN1, PA26, SEST1, Sestrin-1, p53-regulated protein PA26
Immunogen: The antiserum was produced against synthesized peptide derived from human SESN1. AA range:271-320
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 57
GeneID: SESN1
Storage: -20°C/1 year
NOTE: For Research Use Only
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