PAAF1 polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP5062a
Catalog Number: AC-AP5062a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB25789
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB25789
Applications: IHC-P, WB
Datasheet
Request Information
Background:
PAAF1 inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core. In case of HIV-1 infection, recruited by viral Tat to the HIV-1 promoter, where it promotes the recruitment of 19S regulatory complex through dissociation of the proteasome 26S. This presumably promotes provirus transcription efficiency.
Other Names:
Proteasomal ATPase-associated factor 1, Protein G-16, WD repeat-containing protein 71, PAAF1, WDR71
Target/Specificity:
This PAAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from the N-terminal region of human PAAF1.
Antigen Region:
109-138
Antigen Type: Synthetic Peptide
Gene Name: PAAF1
Gene ID: 80227
Primary Accession: Q9BRP4
NCBI Accession: NP_001254732.1;NP_001254733.1;NP_001254734.1;NP_001254735.1;NP_079431.1
Other Accession: Q148I1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
PAAF1 inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core. In case of HIV-1 infection, recruited by viral Tat to the HIV-1 promoter, where it promotes the recruitment of 19S regulatory complex through dissociation of the proteasome 26S. This presumably promotes provirus transcription efficiency.
Other Names:
Proteasomal ATPase-associated factor 1, Protein G-16, WD repeat-containing protein 71, PAAF1, WDR71
Target/Specificity:
This PAAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from the N-terminal region of human PAAF1.
Antigen Region:
109-138
Antigen Type: Synthetic Peptide
Gene Name: PAAF1
Gene ID: 80227
Primary Accession: Q9BRP4
NCBI Accession: NP_001254732.1;NP_001254733.1;NP_001254734.1;NP_001254735.1;NP_079431.1
Other Accession: Q148I1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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