PABPC1 Polyclonal Antibody

Background:
This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
PAB 1, PAB1, PABP 1, PABP1, PABPC 1, PABPC1, PABPC2, PABPL1, Poly A binding protein 1, Poly A binding protein cytoplasmic 1, poly(A) binding protein, cytoplasmic 1, poly(A) binding protein, cytoplasmic 2, Polyadenylate binding protein 1

Immunogen: Recombinant protein of human PABPC1

Swissprot: P11940
Gene Accession: BC015958

Calculated MW: 71 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.6 mg/mL
Dilution: WB 1:200-1:1000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-18611/sc-18610/sc-28834