PACS1 Polyclonal Antibody

Background:
phosphofurin acidic cluster sorting protein 1(PACS1) Homo sapiens This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance. [provided by RefSeq, Jul 2008],

Immunogen: Synthesized peptide derived from human protein . at AA range: 400-480

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 105

GeneID: PACS1 KIAA1175

Storage: -20°C/1 year

NOTE: For Research Use Only